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4dl7
From Proteopedia
Contents |
Human DNA polymerase eta fails to extend primer 2 nucleotide after cisplatin crosslink (Pt-GG4).
Template:ABSTRACT PUBMED 22529383
About this Structure
4dl7 is a 3 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109
Categories: DNA-directed DNA polymerase | Homo sapiens | Biertumpfel, C. | Gregory, M. | Hanaoka, F. | Hua, Y. | Yang, W. | Zhao, Y. | Chemoresistence | Cisplatin | Dna distorsion | Human dna polymerse eta | Inhibition | Kinetic | Molecular splint | Nucleotidyl transfer reaction | Pcna | Second tls polymerase | Transferase-dna-inhibitor complex | Translesion synthesis
