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2qmf

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Revision as of 06:57, 27 July 2012 by OCA (Talk | contribs)
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Image:2qmf.png

Template:STRUCTURE 2qmf

Contents

Structure of BACE Bound to SCH735310

Template:ABSTRACT PUBMED 18023580

About this Structure

2qmf is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Iserloh U, Wu Y, Cumming JN, Pan J, Wang LY, Stamford AW, Kennedy ME, Kuvelkar R, Chen X, Parker EM, Strickland C, Voigt J. Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Bioorg Med Chem Lett. 2008 Jan 1;18(1):414-7. Epub 2007 Nov 6. PMID:18023580 doi:10.1016/j.bmcl.2007.10.116
  • Iserloh U, Pan J, Stamford AW, Kennedy ME, Zhang Q, Zhang L, Parker EM, McHugh NA, Favreau L, Strickland C, Voigt J. Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor. Bioorg Med Chem Lett. 2008 Jan 1;18(1):418-22. Epub 2007 Oct 18. PMID:17980584 doi:10.1016/j.bmcl.2007.10.053

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