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2p7f

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Image:2p7f.png

Template:STRUCTURE 2p7f

Contents

The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme

Template:ABSTRACT PUBMED 17488874

About this Structure

2p7f is a 4 chain structure of Ribozyme. Full crystallographic information is available from OCA.

See Also

Reference

  • Torelli AT, Krucinska J, Wedekind JE. A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization. RNA. 2007 Jul;13(7):1052-70. Epub 2007 May 8. PMID:17488874 doi:rna.510807
  • Salter J, Krucinska J, Alam S, Grum-Tokars V, Wedekind JE. Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transfer. Biochemistry. 2006 Jan 24;45(3):686-700. PMID:16411744 doi:10.1021/bi051887k
  • Alam S, Grum-Tokars V, Krucinska J, Kundracik ML, Wedekind JE. Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn. Biochemistry. 2005 Nov 8;44(44):14396-408. PMID:16262240 doi:10.1021/bi051550i

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