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2f3f

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Revision as of 07:26, 27 July 2012 by OCA (Talk | contribs)
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Image:2f3f.png

Template:STRUCTURE 2f3f

Contents

Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor

Template:ABSTRACT PUBMED 16854060

About this Structure

2f3f is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M. Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J Med Chem. 2006 Jul 27;49(15):4544-67. PMID:16854060 doi:10.1021/jm060154a

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OCA

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