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3dyf

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Image:3dyf.png

Template:STRUCTURE 3dyf

Contents

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461 and Isopentyl Diphosphate

Template:ABSTRACT PUBMED 19309137

About this Structure

3dyf is a 2 chain structure of Farnesyl diphosphate synthase with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

See Also

Reference

  • Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, Chang TK, Lin FY, Van Beek E, Papapoulos S, Wang AH, Kubo T, Ochi M, Mukkamala D, Oldfield E. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. J Am Chem Soc. 2009 Apr 15;131(14):5153-62. PMID:19309137 doi:10.1021/ja808285e

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