3kxm

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Template:STRUCTURE 3kxm

Contents

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor K74

Template:ABSTRACT PUBMED 21513497

About this Structure

3kxm is a 1 chain structure of Casein kinase with sequence from Zea mays. Full crystallographic information is available from OCA.

See Also

Reference

  • Sarno S, Papinutto E, Franchin C, Bain J, Elliott M, Meggio F, Kazimierczuk Z, Orzeszko A, Zanotti G, Battistutta R, Pinna LA. Atp Site-Directed Inhibitors of Protein Kinase Ck2: An Update. Curr Top Med Chem. 2011 Mar 29. PMID:21513497
  • Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem Biol. 2005 Nov;12(11):1211-9. PMID:16298300 doi:10.1016/j.chembiol.2005.08.015
  • Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307

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