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1sl2

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Image:1sl2.png

Template:STRUCTURE 1sl2

Contents

Ternary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template and an incoming nucleotide

Template:ABSTRACT PUBMED 15235589

About this Structure

1sl2 is a 4 chain structure of DNA polymerase and Thioredoxin with sequence from Enterobacteria phage t7 and Escherichia coli. The July 2007 RCSB PDB Molecule of the Month feature on Thymine Dimers by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_7. Full crystallographic information is available from OCA.

See Also

Reference

  • Li Y, Dutta S, Doublie S, Bdour HM, Taylor JS, Ellenberger T. Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Nat Struct Mol Biol. 2004 Aug;11(8):784-90. Epub 2004 Jul 4. PMID:15235589 doi:http://dx.doi.org/10.1038/nsmb792

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