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1nz7

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Image:1nz7.png

Template:STRUCTURE 1nz7

Contents

POTENT, SELECTIVE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B USING A SECOND PHOSPHOTYROSINE BINDING SITE, complexed with compound 19.

Template:ABSTRACT PUBMED 12749891

About this Structure

1nz7 is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Xin Z, Oost TK, Abad-Zapatero C, Hajduk PJ, Pei Z, Szczepankiewicz BG, Hutchins CW, Ballaron SJ, Stashko MA, Lubben T, Trevillyan JM, Jirousek MR, Liu G. Potent, selective inhibitors of protein tyrosine phosphatase 1B. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1887-90. PMID:12749891
  • Wiesmann C, Barr KJ, Kung J, Zhu J, Erlanson DA, Shen W, Fahr BJ, Zhong M, Taylor L, Randal M, McDowell RS, Hansen SK. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struct Mol Biol. 2004 Aug;11(8):730-7. Epub 2004 Jul 18. PMID:15258570 doi:10.1038/nsmb803

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