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2p8h

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Image:2p8h.png

Template:STRUCTURE 2p8h

Contents

Crystal structure of human beta secretase complexed with inhibitor

About this Structure

2p8h is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP. Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1. ChemMedChem. 2007 Jul;2(7):995-9. PMID:17458843 doi:10.1002/cmdc.200700038

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