1nhv
From Proteopedia
Contents |
Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor
Template:ABSTRACT PUBMED 12509436
About this Structure
1nhv is a 2 chain structure of Nonstructural protein and RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.
See Also
Reference
- Wang M, Ng KK, Cherney MM, Chan L, Yannopoulos CG, Bedard J, Morin N, Nguyen-Ba N, Alaoui-Ismaili MH, Bethell RC, James MN. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. J Biol Chem. 2003 Mar 14;278(11):9489-95. Epub 2002 Dec 30. PMID:12509436 doi:10.1074/jbc.M209397200
Categories: Hepatitis c virus subtype 1b | RNA-directed RNA polymerase | Alaoui-Ismaili, M H. | Bedard, J. | Bethell, R C. | Chan, L. | Cherney, M M. | James, M N.G. | Morin, N. | Ng, K K.S. | Nguyen-Ba, N. | Wang, M. | Yannopoulos, C G. | Enzyme inhibition | Hepatitis c | Rna polymerase | Transferase