2iej

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2iej

Contents 1 Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A Resolution 2 About this Structure 3 See Also 4 Reference

Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A Resolution

Template:ABSTRACT PUBMED 17208314

About this Structure

2iej is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Farnesyltransferase

Reference

• Eastman RT, White J, Hucke O, Yokoyama K, Verlinde CL, Hast MA, Beese LS, Gelb MH, Rathod PK, Van Voorhis WC. Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. Mol Biochem Parasitol. 2007 Mar;152(1):66-71. Epub 2006 Dec 22. PMID:17208314 doi:10.1016/j.molbiopara.2006.11.012