2qlq
From Proteopedia
Contents |
Crystal structure of SRC kinase domain with covalent inhibitor RL3
Template:ABSTRACT PUBMED 18316192
About this Structure
2qlq is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Gruetter, C. | Michalczyk, A. | Rauh, D. | Rode, H B. | Atp-binding | Drug resistance | Irreversible inhibitor | Kovalent inhibitor | Lipoprotein | Myristate | Nucleotide-binding | Phosphorylation | Proto-oncogene | Sh2 domain | Sh3 domain | Src kinase domain | Transferase | Tyrosine-protein kinase
