1nl2

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Template:STRUCTURE 1nl2

Contents 1 BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM AND LYSOPHOSPHOTIDYLSERINE 2 About this Structure 3 See Also 4 Reference

BOVINE PROTHROMBIN FRAGMENT 1 IN COMPLEX WITH CALCIUM AND LYSOPHOSPHOTIDYLSERINE

Template:ABSTRACT PUBMED 12923575

About this Structure

1nl2 is a 1 chain structure of Thrombin with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

• Thrombin

Reference

• Huang M, Rigby AC, Morelli X, Grant MA, Huang G, Furie B, Seaton B, Furie BC. Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Nat Struct Biol. 2003 Sep;10(9):751-6. Epub 2003 Aug 17. PMID:12923575 doi:http://dx.doi.org/10.1038/nsb971
• Lemmon MA. Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol. 2008 Feb;9(2):99-111. PMID:18216767 doi:10.1038/nrm2328
• Rodriguez Y, Mezei M, Osman R. The PT1-Ca2+ Gla domain binds to a membrane through two dipalmitoylphosphatidylserines. A computational study. Biochemistry. 2008 Dec 16;47(50):13267-78. PMID:19086158