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1oyt

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Image:1oyt.png

Template:STRUCTURE 1oyt

Contents

COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED FLUORINATED INHIBITOR

About this Structure

1oyt is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Olsen JA, Banner DW, Seiler P, Obst Sander U, D'Arcy A, Stihle M, Muller K, Diederich F. A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions. Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2507-11. PMID:12800172 doi:10.1002/anie.200351268

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OCA

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