3b2u
From Proteopedia
Contents |
Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Template:ABSTRACT PUBMED 18275813
About this Structure
3b2u is a 24 chain structure of Antibody and Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Kussie P, Ferguson KM. Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. Structure. 2008 Feb;16(2):216-27. PMID:18275813 doi:10.1016/j.str.2007.11.009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Ferguson, K M. | Kussie, P. | Li, S. | Anti-oncogene | Antigen:antibody complex | Antitumor | Atp-binding | Cell cycle | Cell surface receptor | Disease mutation | Drug | Fab fragment | Glycoprotein | Immune system-transferase complex | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase
