1gw6

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Template:STRUCTURE 1gw6

Contents 1 STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT 2 About this Structure 3 See Also 4 Reference

STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT

Template:ABSTRACT PUBMED 11917124

About this Structure

1gw6 is a 1 chain structure of Leukotriene A4 Hydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Leukotriene A4 Hydrolase

Reference

• Rudberg PC, Tholander F, Thunnissen MM, Samuelsson B, Haeggstrom JZ. Leukotriene A4 hydrolase: selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4215-20. Epub 2002 Mar 26. PMID:11917124 doi:10.1073/pnas.072090099
• Thunnissen MM, Nordlund P, Haeggstrom JZ. Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation. Nat Struct Biol. 2001 Feb;8(2):131-5. PMID:11175901 doi:10.1038/84117