4aw5

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Template:STRUCTURE 4aw5

Complex of the EphB4 kinase domain with an oxindole inhibitor

Template:ABSTRACT PUBMED 22765894

About this Structure

4aw5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kim MH, Tsuhako AL, Co EW, Aftab DT, Bentzien F, Chen J, Cheng W, Engst S, Goon L, Klein RR, Le DT, Mac M, Parks JJ, Qian F, Rodriquez M, Stout TJ, Till JH, Won KA, Wu X, Michael Yakes F, Yu P, Zhang W, Zhao Y, Lamb P, Nuss JM, Xu W. The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2012 Aug 1;22(15):4979-85. Epub 2012 Jun 16. PMID:22765894 doi:10.1016/j.bmcl.2012.06.029

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