3v9t

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Image:3v9t.png

Template:STRUCTURE 3v9t

Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator

Template:ABSTRACT PUBMED 22225641

About this Structure

3v9t is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Furukawa A, Arita T, Fukuzaki T, Satoh S, Mori M, Honda T, Matsui Y, Wakabayashi K, Hayashi S, Araki K, Ohsumi J. Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARgamma partial agonists. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1348-51. Epub 2011 Dec 16. PMID:22225641 doi:10.1016/j.bmcl.2011.12.066

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