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3r7o

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Image:3r7o.png

Template:STRUCTURE 3r7o

Structure of dually phosphorylated c-Met in complex with MK-2461

Template:ABSTRACT PUBMED 21247903

About this Structure

3r7o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rickert KW, Patel SB, Allison TJ, Byrne NJ, Darke PL, Ford RE, Guerin DJ, Hall DL, Kornienko M, Lu J, Munshi SK, Reid JC, Shipman JM, Stanton EF, Wilson KJ, Young JR, Soisson SM, Lumb KJ. Structural basis for selective small molecule kinase inhibition of activated c-Met. J Biol Chem. 2011 Apr 1;286(13):11218-25. Epub 2011 Jan 18. PMID:21247903 doi:10.1074/jbc.M110.204404

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