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3tti

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Revision as of 10:28, 8 August 2012 by OCA (Talk | contribs)
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Image:3tti.png

Template:STRUCTURE 3tti

Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor

Template:ABSTRACT PUBMED 22244937

About this Structure

3tti is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Plantevin Krenitsky V, Nadolny L, Delgado M, Ayala L, Clareen SS, Hilgraf R, Albers R, Hegde S, D'Sidocky N, Sapienza J, Wright J, McCarrick M, Bahmanyar S, Chamberlain P, Delker SL, Muir J, Giegel D, Xu L, Celeridad M, Lachowitzer J, Bennett B, Moghaddam M, Khatsenko O, Katz J, Fan R, Bai A, Tang Y, Shirley MA, Benish B, Bodine T, Blease K, Raymon H, Cathers BE, Satoh Y. Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1433-8. Epub 2011 Dec 10. PMID:22244937 doi:10.1016/j.bmcl.2011.12.027

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