1jf7

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Template:STRUCTURE 1jf7

Contents 1 HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836 2 About this Structure 3 See Also 4 Reference

HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836

Template:ABSTRACT PUBMED 11806712

About this Structure

1jf7 is a 2 chain structure of Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Tyrosine phosphatase

Reference

• Larsen SD, Barf T, Liljebris C, May PD, Ogg D, O'Sullivan TJ, Palazuk BJ, Schostarez HJ, Stevens FC, Bleasdale JE. Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B. J Med Chem. 2002 Jan 31;45(3):598-622. PMID:11806712
• Wiesmann C, Barr KJ, Kung J, Zhu J, Erlanson DA, Shen W, Fahr BJ, Zhong M, Taylor L, Randal M, McDowell RS, Hansen SK. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struct Mol Biol. 2004 Aug;11(8):730-7. Epub 2004 Jul 18. PMID:15258570 doi:10.1038/nsmb803