1iiu
From Proteopedia
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Chicken plasma retinol-binding protein (RBP)
Overview
The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a=46.06(5) A, b=53.56(6) A, c=73.41(8) A, and one protein molecule in the asymmetric unit). Despite being obtained from a species phylogenetically distant from mammals, chicken holoRBP has an overall structure that closely resembles the previously determined structures of mammalian holoRBPs. The lack in chicken RBP of eight carboxy-terminal amino acid residues characteristic of mammalian RBPs does not significantly affect the protein structure. A distinctive feature of the avian protein is a better definition of the loop 63-67, close to the opening of the beta-barrel cavity accommodating the retinol molecule, which is rather disordered in the structures of mammalian RBPs.
About this Structure
1IIU is a Single protein structure of sequence from Gallus gallus with and as ligands. Full crystallographic information is available from OCA.
Reference
Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:11738088
Page seeded by OCA on Thu Feb 21 13:12:22 2008
Categories: Gallus gallus | Single protein | Berni, R. | Calderone, V. | Zanotti, G. | CD | RTL | Rbp | Retinol
