3upa

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Template:STRUCTURE 3upa

A general strategy for the generation of human antibody variable domains with increased aggregation resistance

Template:ABSTRACT PUBMED 22745168

About this Structure

3upa is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dudgeon K, Rouet R, Kokmeijer I, Schofield P, Stolp J, Langley D, Stock D, Christ D. General strategy for the generation of human antibody variable domains with increased aggregation resistance. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10879-84. Epub 2012 Jun 27. PMID:22745168 doi:10.1073/pnas.1202866109

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