4ael

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Template:STRUCTURE 4ael

PDE10A in complex with the inhibitor AZ5

Template:ABSTRACT PUBMED 22321214

About this Structure

4ael is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Bauer U, Giordanetto F, Bauer M, O'Mahony G, Johansson KE, Knecht W, Hartleib-Geschwindner J, Carlsson ET, Enroth C. Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1944-8. Epub 2012 Jan 26. PMID:22321214 doi:10.1016/j.bmcl.2012.01.046

Proteopedia Page Contributors and Editors (what is this?)

Retrieved from "http://52.214.119.220/wiki/index.php/4ael"

Categories: Homo sapiens | Bauer, M. | Bauer, U. | Carlsson, E Toppner. | Enroth, C. | Giordanetto, F. | Hartleib-Geschwindner, J. | Johansson, K E. | Knecht, W. | Omahony, G. | Sjogren, T. | Enzyme inhibitor | Hit-to-lead | Hydrolase | Naphtyridine

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