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4ael

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Revision as of 04:53, 15 August 2012 by OCA (Talk | contribs)
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Image:4ael.png

Template:STRUCTURE 4ael

PDE10A in complex with the inhibitor AZ5

Template:ABSTRACT PUBMED 22321214

About this Structure

4ael is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bauer U, Giordanetto F, Bauer M, O'Mahony G, Johansson KE, Knecht W, Hartleib-Geschwindner J, Carlsson ET, Enroth C. Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1944-8. Epub 2012 Jan 26. PMID:22321214 doi:10.1016/j.bmcl.2012.01.046

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OCA

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