4ezh

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Template:STRUCTURE 4ezh

the crystal structure of KDM6B bound with H3K27me3 peptide

Template:ABSTRACT PUBMED 22842901

About this Structure

4ezh is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Kruidenier L, Chung CW, Cheng Z, Liddle J, Che K, Joberty G, Bantscheff M, Bountra C, Bridges A, Diallo H, Eberhard D, Hutchinson S, Jones E, Katso R, Leveridge M, Mander PK, Mosley J, Ramirez-Molina C, Rowland P, Schofield CJ, Sheppard RJ, Smith JE, Swales C, Tanner R, Thomas P, Tumber A, Drewes G, Oppermann U, Patel DJ, Lee K, Wilson DM. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Jul 29. doi: 10.1038/nature11262. PMID:22842901 doi:10.1038/nature11262

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