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From Proteopedia
Outer Surface Protein A (OspA)
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Outer surface protein A (OspA) is a major lipoprotein[1]on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions such as late stage neurological disorders that are associated with Lyme Disease.
