3tub

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Image:3tub.jpg

Template:STRUCTURE 3tub

Crystal structure of SYK kinase domain with 1-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-3-((1R,2S)-2-phenylcyclopropyl)urea

Template:ABSTRACT PUBMED 22759374

About this Structure

3tub is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lovering F, McDonald J, Whitlock GA, Glossop PA, Phillips C, Bent A, Sabnis Y, Ryan M, Fitz L, Lee J, Chang JS, Han S, Kurumbail R, Thorarensen A. Identification of Type-II Inhibitors Using Kinase Structures. Chem Biol Drug Des. 2012 Jul 3. doi: 10.1111/j.1747-0285.2012.01443.x. PMID:22759374 doi:10.1111/j.1747-0285.2012.01443.x

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OCA

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