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3ugc

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Revision as of 05:11, 29 August 2012 by OCA (Talk | contribs)
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Image:3ugc.png

Template:STRUCTURE 3ugc

Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594

Template:ABSTRACT PUBMED 22684457

About this Structure

3ugc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Andraos R, Qian Z, Bonenfant D, Rubert J, Vangrevelinghe E, Scheufler C, Marque F, Regnier CH, De Pover A, Ryckelynck H, Bhagwat N, Koppikar P, Goel A, Wyder L, Tavares G, Baffert F, Pissot-Soldermann C, Manley PW, Gaul C, Voshol H, Levine RL, Sellers WR, Hofmann F, Radimerski T. Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent. Cancer Discov. 2012 Jun;2(6):512-23. Epub 2012 May 3. PMID:22684457 doi:10.1158/2159-8290.CD-11-0324

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