4dii
From Proteopedia
X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions
Template:ABSTRACT PUBMED 22669903
About this Structure
4dii is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res. 2012 Jun 4. PMID:22669903 doi:10.1093/nar/gks512
- Russo Krauss I, Merlino A, Giancola C, Randazzo A, Mazzarella L, Sica F. Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res. 2011 Sep 1;39(17):7858-67. Epub 2011 Jun 28. PMID:21715374 doi:10.1093/nar/gkr522
- Padmanabhan K, Padmanabhan KP, Ferrara JD, Sadler JE, Tulinsky A. The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. J Biol Chem. 1993 Aug 25;268(24):17651-4. PMID:8102368
- Padmanabhan K, Tulinsky A. An ambiguous structure of a DNA 15-mer thrombin complex. Acta Crystallogr D Biol Crystallogr. 1996 Mar 1;52(Pt 2):272-82. PMID:15299700 doi:10.1107/S0907444995013977
