1ksn

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Template:STRUCTURE 1ksn

Contents

Crystal Structure of Human Coagulation Factor XA Complexed with FXV673

Template:ABSTRACT PUBMED 12039587

About this Structure

1ksn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Guertin KR, Gardner CJ, Klein SI, Zulli AL, Czekaj M, Gong Y, Spada AP, Cheney DL, Maignan S, Guilloteau JP, Brown KD, Colussi DJ, Chu V, Heran CL, Morgan SR, Bentley RG, Dunwiddie CT, Leadley RJ, Pauls HW. Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1671-4. PMID:12039587

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