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2vdo

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Image:2vdo.png

Template:STRUCTURE 2vdo

Contents

INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQAGDV

Template:ABSTRACT PUBMED 18710925

About this Structure

2vdo is a 5 chain structure with sequence from Homo sapiens and Mus musculus. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.

See Also

Reference

  • Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. J Cell Biol. 2008 Aug 25;182(4):791-800. Epub 2008 Aug 18. PMID:18710925 doi:jcb.200801146
  • Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:http://dx.doi.org/10.1038/nature02976

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