3mhc

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Template:STRUCTURE 3mhc

Contents 1 Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket 2 About this Structure 3 See Also 4 Reference

Crystal structure of human cabonic anhydrase II in adduct with an adamantyl analogue of acetazolamide in a novel hydrophobic binding pocket

Template:ABSTRACT PUBMED 20605094

About this Structure

3mhc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Carbonic anhydrase

Reference

• Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4376-81. Epub 2010 Jun 17. PMID:20605094 doi:10.1016/j.bmcl.2010.06.082