3dm6

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Image:3dm6.png

Template:STRUCTURE 3dm6

Contents

Beta-secretase 1 complexed with statine-based inhibitor

Template:ABSTRACT PUBMED 18842420

About this Structure

3dm6 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B. Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues. Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420 doi:S0968-0896(08)00877-8

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