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2zc9
From Proteopedia
Contents |
Thrombin in complex with Inhibitor
Template:ABSTRACT PUBMED 19520086
About this Structure
2zc9 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Baum B, Muley L, Heine A, Smolinski M, Hangauer D, Klebe G. Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin. J Mol Biol. 2009 Aug 21;391(3):552-64. Epub 2009 Jun 9. PMID:19520086 doi:10.1016/j.jmb.2009.06.016
- Baum B, Mohamed M, Zayed M, Gerlach C, Heine A, Hangauer D, Klebe G. More than a simple lipophilic contact: a detailed thermodynamic analysis of nonbasic residues in the s1 pocket of thrombin. J Mol Biol. 2009 Jul 3;390(1):56-69. Epub 2009 May 3. PMID:19409395 doi:10.1016/j.jmb.2009.04.051
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Baum, B. | Heine, A. | Klebe, G. | Acute phase | Blood clotting-hydrolase inhibitor complex | Blood clotting/serine protease inhibitor | Blood coagulation | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Secreted | Sulfation | Zymogen
