2hwh

From Proteopedia

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Template:STRUCTURE 2hwh

Contents 1 HCV NS5B allosteric inhibitor complex 2 About this Structure 3 See Also 4 Reference

HCV NS5B allosteric inhibitor complex

Template:ABSTRACT PUBMED 16934455

About this Structure

2hwh is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

See Also

• RNA polymerase

Reference

• Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N. Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. Epub 2006 Aug 24. PMID:16934455 doi:10.1016/j.bmcl.2006.08.056