This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1izi
From Proteopedia
Contents |
Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants
Template:ABSTRACT PUBMED 12460574
About this Structure
1izi is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Weber J, Mesters JR, Lepsik M, Prejdova J, Svec M, Sponarova J, Mlcochova P, Skalicka K, Strisovsky K, Uhlikova T, Soucek M, Machala L, Stankova M, Vondrasek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains. J Mol Biol. 2002 Dec 6;324(4):739-54. PMID:12460574
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Hilgenfeld, R. | Klimkait, T. | Konvalinka, J. | Kraeusslich, H G. | Lepsik, M. | Machala, L. | Mesters, J R. | Mlcochova, P. | Prejdova, J. | Skalicka, K. | Soucek, M. | Sponarova, J. | Stankova, M. | Strisovsky, K. | Svec, M. | Uhlikova, T. | Vondrasek, J. | Weber, J. | Hiv-1 proteinase | Hydrolase | Potent inhibitor | Subsite binding | Triple mutant
