2fx7

From Proteopedia

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Template:STRUCTURE 2fx7

Contents 1 Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41 2 About this Structure 3 See Also 4 Reference

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41

Template:ABSTRACT PUBMED 17125793

About this Structure

2fx7 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Antibody

Reference

• Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:17125793 doi:10.1016/j.jmb.2006.10.088
• Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 2005 Feb;22(2):163-73. PMID:15723805 doi:10.1016/j.immuni.2004.12.011