3okj
From Proteopedia
Contents |
Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition
About this Structure
3okj is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Grawert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. PMID:21154547 doi:10.1002/anie.201005488
Categories: Proteasome endopeptidase complex | Saccharomyces cerevisiae | Gallastegui, P. | Groll, M. | Huber, R. | Kloetzel, PM. | Poynor, M. | Schmidt, B. | Stein, M. | Central antiparallel beta-sheet flanked by helice | Cytosol | Hydrolase-hydrolase inhibitor complex | Inhibitor | Nucleus | Protease | Turnover of ubiquitinated substrate | Ubiquitin