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3jwq

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Image:3jwq.png

Template:STRUCTURE 3jwq

Contents

Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil

Template:ABSTRACT PUBMED 19798052

About this Structure

3jwq is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Barren B, Gakhar L, Muradov H, Boyd KK, Ramaswamy S, Artemyev NO. Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit. EMBO J. 2009 Nov 18;28(22):3613-22. Epub 2009 Oct 1. PMID:19798052 doi:10.1038/emboj.2009.284
  • Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. Structural characterization of the rod cGMP phosphodiesterase 6. J Mol Biol. 2010 Aug 20;401(3):363-73. Epub 2010 Jul 1. PMID:20600113 doi:10.1016/j.jmb.2010.06.044

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