This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3l8x
From Proteopedia
Contents |
P38 alpha kinase complexed with a pyrazolo-pyrimidine based inhibitor
Template:ABSTRACT PUBMED 18359226
About this Structure
3l8x is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3cg2. Full crystallographic information is available from OCA.
See Also
Reference
- Das J, Moquin RV, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2652-7. Epub 2008 Mar 10. PMID:18359226 doi:10.1016/j.bmcl.2008.03.019
