1e35

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Template:STRUCTURE 1e35

Contents 1 PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-TOLUENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR TWO MINUTES 2 About this Structure 3 See Also 4 Reference

PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-TOLUENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR TWO MINUTES

Template:ABSTRACT PUBMED 11023818

About this Structure

1e35 is a 1 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

• Elastase

Reference

• Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. 'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes. Biochem J. 2000 Oct 15;351 Pt 2:335-40. PMID:11023818
• Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 1999 Jun 22;38(25):7989-98. PMID:10387042 doi:10.1021/bi990098y
• Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 1998 Dec 15;37(50):17506-13. PMID:9860865 doi:10.1021/bi9816249