1sme

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Image:1sme.png

Template:STRUCTURE 1sme

Contents

PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A

Template:ABSTRACT PUBMED 8816746

About this Structure

1sme is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

Reference

  • Silva AM, Lee AY, Gulnik SV, Maier P, Collins J, Bhat TN, Collins PJ, Cachau RE, Luker KE, Gluzman IY, Francis SE, Oksman A, Goldberg DE, Erickson JW. Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10034-9. PMID:8816746
  • Joshi AA, Viswanathan CL. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials. Bioorg Med Chem Lett. 2006 May 15;16(10):2613-7. Epub 2006 Mar 3. PMID:16516468 doi:10.1016/j.bmcl.2006.02.038

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