3gw5
From Proteopedia
Contents |
Crystal structure of human renin complexed with a novel inhibitor
Template:ABSTRACT PUBMED 19457666
About this Structure
3gw5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tice CM, Xu Z, Yuan J, Simpson RD, Cacatian ST, Flaherty PT, Zhao W, Guo J, Ishchenko A, Singh SB, Wu Z, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Muller D, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Design and optimization of renin inhibitors: Orally bioavailable alkyl amines. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3541-5. Epub 2009 May 5. PMID:19457666 doi:10.1016/j.bmcl.2009.04.140
Categories: Homo sapiens | Renin | McKeever, B M. | Wu, Z. | Aspartate protease | Aspartyl protease | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Hypertension | Membrane | Protease | Renin expression | Renin inhibitor | Secreted | Zymogen
