1tl3

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Image:1tl3.png

Template:STRUCTURE 1tl3

Contents

Crystal structure of hiv-1 reverse transcriptase in complex with gw450557

Template:ABSTRACT PUBMED 15537346

About this Structure

1tl3 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J Med Chem. 2004 Nov 18;47(24):5912-22. PMID:15537346 doi:10.1021/jm040071z
  • Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588

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