2pfh

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Template:STRUCTURE 2pfh

Contents

Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.

Template:ABSTRACT PUBMED 22752989

About this Structure

2pfh is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Cousido-Siah A, Petrova T, Hazemann I, Mitschler A, Ruiz FX, Howard E, Ginell S, Atmanene C, Van Dorsselaer A, Sanglier-Cianferani S, Joachimiak A, Podjarny A. Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins. 2012 Jul 2. doi: 10.1002/prot.24136. PMID:22752989 doi:10.1002/prot.24136

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