3h59
From Proteopedia
Contents |
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2
Template:ABSTRACT PUBMED 19700319
About this Structure
3h59 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Zhao J, Elworthy TR, Tracy J, Chin E, Li J, Lui A, Wang B, Oshiro C, Harris SF, Ghate M, Leveque VJ, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Fitch B, Brandl M, Masjedizadeh M, Wu SY, de Keczer S, Voronin T. Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5648-51. Epub 2009 Aug 8. PMID:19700319 doi:10.1016/j.bmcl.2009.08.023
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Ghate, M. | Harris, S F. | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Disulfide bond | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Hcv | Helicase | Hepatitis | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Ns5b | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transferase rna-dependent rna polymerase | Transmembrane | Viral nucleoprotein | Virion
