3roc

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Image:3roc.png

Template:STRUCTURE 3roc

Contents

Crystal structure of human p38 alpha complexed with a pyrimidinone compound

Template:ABSTRACT PUBMED 21620699

About this Structure

3roc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Devadas B, Selness SR, Xing L, Madsen HM, Marrufo LD, Shieh H, Messing DM, Yang JZ, Morgan HM, Anderson GD, Webb EG, Zhang J, Devraj RV, Monahan JB. Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3856-60. Epub 2011 May 8. PMID:21620699 doi:10.1016/j.bmcl.2011.05.006

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