1mu8
From Proteopedia
Contents |
thrombin-hirugen_l-378,650
Template:ABSTRACT PUBMED 12570369
About this Structure
1mu8 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J Med Chem. 2003 Feb 13;46(4):461-73. PMID:12570369 doi:http://dx.doi.org/10.1021/jm020311f
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Barrow, J C. | Bohn, D. | Burgey, C S. | Chen, Z. | Clayton, F C. | Coburn, C A. | Cook, J J. | Detwiler, T J. | Dorsey, B D. | Gardell, S J. | Holahan, M A. | Krueger, J A. | Kuo, L. | Leonard, Y M. | Lewis, S D. | Lucas, B J. | Lyle, E A. | Lyle, T A. | Lynch, J J. | McDonough, C M. | McMasters, D R. | Miller-Stein, C. | Robinson, K A. | Sanders, W M. | Sanderson, P E. | Shafer, J A. | Singh, R. | Sitko, G R. | Stranieri, M T. | Vacca, J P.J. | Wallace, A A. | White, R B. | Williams, P D. | Wong, B. | Yan, Y. | Blood clotting | Hydrolase-hydrolase inhibitor complex | Thrombin-hirugen
