2ftd

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2ftd

Contents 1 Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound 2 About this Structure 3 See Also 4 Reference

Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound

Template:ABSTRACT PUBMED 16509577

About this Structure

2ftd is a 2 chain structure with sequence from Macaca mulatta. Full crystallographic information is available from OCA.

See Also

• Cathepsin

Reference

• Yamashita DS, Marquis RW, Xie R, Nidamarthy SD, Oh HJ, Jeong JU, Erhard KF, Ward KW, Roethke TJ, Smith BR, Cheng HY, Geng X, Lin F, Offen PH, Wang B, Nevins N, Head MS, Haltiwanger RC, Narducci Sarjeant AA, Liable-Sands LM, Zhao B, Smith WW, Janson CA, Gao E, Tomaszek T, McQueney M, James IE, Gress CJ, Zembryki DL, Lark MW, Veber DF. Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors. J Med Chem. 2006 Mar 9;49(5):1597-612. PMID:16509577 doi:10.1021/jm050915u