2opr

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Template:STRUCTURE 2opr

Contents 1 Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X. 2 About this Structure 3 See Also 4 Reference

Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.

Template:ABSTRACT PUBMED 17441703

About this Structure

2opr is a 2 chain structure with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

See Also

• Reverse transcriptase

Reference

• Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. J Med Chem. 2007 May 17;50(10):2301-9. Epub 2007 Apr 19. PMID:17441703 doi:http://dx.doi.org/10.1021/jm061117m